MASCO Corporation


Short-term LDL cholesterol-lowering efficacy of plant stanol esters.

The short-term cholesterol-lowering efficacy of plant stanol esters has been open to debate, and the data from different clinical studies with hypercholesterolemic subjects are variable, partly due to lack of systematic studies. Therefore, we investigated the time in days needed to obtain the full cholesterol-lowering effect of stanol esters in hypercholesterolemic subjects.
Eleven mildly to moderately hypercholesterolemic subjects consumed stanol ester margarine (2.0 g/day of stanols) as a part of their habitual diet for 14 days and the changes in serum lipid values were measured three times at 4, 8 and 15 days after the initiation of test margarine consumption (0 day). The returning of serum lipid concentrations to baseline was measured two times after 2 or 3 days and after 7 days of the end of the test margarine consumption.
Serum LDL cholesterol concentrations were reduced from 0 day (4.51 +/- 0.66 mmol/l) by 3.5% (P = ns), 9.9% (p < 0.05) and 10.2% (P < 0.05) at 4, 8 and 15 days, respectively. Serum campesterol/total cholesterol ratio, an indirect marker of intestinal cholesterol absorption, was significantly reduced on day 4 already. After ending the stanol ester use serum cholesterol concentrations began to return rapidly and after 7 days serum LDL cholesterol was 5.3% less than the initial value (P = ns).
The specific effect of plant stanol esters on serum LDL cholesterol can fully be obtained within 1-2 weeks of the use of plant stanol ester-enriched margarine



Management Info:

Designed By: Storyberry Corporation

Powered By: Google Inc.

Privacy Policy: JDF Corporation

Terms of Use: BPF Corporation

Merchant Processor: Donation

RSS Health Topics

  • Nutrition – Facts | Health | Definition Terms
    NUTRITION. Food is comprised of nutrients that are classified by their role in the body: the energy-yielding macronutrients (carbohydrates, protein, and fat), the essential micronutrients (vitamins, minerals, and water), and numerous … Continue reading →
    Definition Varicose veins are dilated, tortuous, elongated superficial veins that are usually seen in the legs. Description Varicose veins, also called varicosities, are mostly often on the legs, although they can be found in other parts of the body. Mostly they appear as lumpy, winding vessels just below the surface of the skin. There are three types of vei […]
  • Cryotherapy
    Cryotherapy Definition Cryotherapy is a technique that uses an extremely cold liquid or instrument to freeze and destroy abnormal skin cells that require removal. It is a freezing substance or … Continue reading →
  • Exercise Therapy
      Exercise Therapy Definition Exercises is physical activity that is planned, structured and repetitive for the purpose of conditioning any part of the body. Exercise is utilized to improve health, … Continue reading →
  • Coronary Heart Disease – Diagnosis and Treatments
    Coronary Heart Disease Methods of Diagnosis Your healthcare provider diagnoses coronary artery disease (atherosclerosis) based on your medical and family histories, a physical exam, or results from the following tests. … Continue reading →


Stat Counter

Hours & Info

+1-313-2747400 (Phone) +1-313-7924177 (Fax)
Lunch Break: 11am - 1pm

Other Phone Number(s)


RSS MASCO Construction

%d bloggers like this: